Liver Tests

Liver function tests are  blood tests designed to give information about the state of a patient's liver. The parameters measured include  albumin, billirubin and others. Liver transaminases(AST/ALT (SGOT/SGPT) are biomarkers of liver injury in a patient with some degree of intact liver function.

Albumin and Globulin

Albumin and globulin are our two main blood proteins made specifically by the liver.  One of their functions is to gie your blood osmotic force so water will stay in the blood vessels rather than seep into the tissues. Albumin is more effective and is, therefore more important. There is more than one kind of globulin, they are also your antibodies. The totaI of albumin plus all your globulin is called total protein (T.p.). It should reach a value of about seven: 7.5 is better, this assures good osmotic strength. Albumin levels are decreased in chronic liver disease, such as cirrhosis.

Cobalt, vanadium, malonate  and dyes are the chief culprits in disturbing albumin and globulin levels. They can come from plastic and metal tooth restorations.

If the liver is injured chemically, cells die and release enzymes into the blood stream. Three common enzymes are:

1. Alanine transaminase (ALT): Alanine transaminase (ALT), also called Serum Glutamic Pyruvate Transaminase (SGPT) or Alanine aminotransferase (ALAT) is an enzyme present in hepatocytes (liver cells). When a cell is damaged, it leaks this enzyme into the blood, where it is measured. ALT rises dramatically in acute liver damage, such as viral hepatitis or paracetamol (acetaminophen) overdose. Remove lead.
2. Aspartate transaminase (AST): Aspartate transaminase (AST) also called Serum Glutamic Oxaloacetic Transaminase (SGOT) or aspartate aminotransferase (ASAT) is similar to ALT in that it is another enzyme associated with liver parenchymal cells. It is raised in acute liver damage, but is also present in red blood cells, and cardiac and skeletal muscle and is therefore not specific to the liver.  Remove lead.
3. Gamma glutamyl transpeptidase (GGT): Although reasonably specific to the liver and a more sensitive marker for cholestatic damage than ALP, Gamma glutamyl transpeptidase (GGT) may be elevated with even minor, sub-clinical levels of liver dysfunction.  If GGT is too high , it can be caused by DAB dye, strontium and CMV.

When transaminases go up a liver toxin is usually present such as lead found usually in drugs or supplements. All three enzymes should be below 25 U/L.

Alkaline phosphatase (ALP)

Alkaline phosphatase (ALP) is an enzyme in the cells lining the biliary ducts of the liver. ALP levels in plasma will rise with large bile duct obstruction, intrahepatic cholestasis or infiltrative diseases of the liver. ALP is also present in bone and placental tissue, so it is higher in growing children (as their bones are being remodelled) and elderly patients with Paget's disease.

If alk phos is too low remove cobalt, sudan black, fast garnet dyes in liver and WBCs

If alk phos is too high remove DAB dye in WBCs.

Total bilirubin (TBIL)

Bilirubin is a breakdown product of haem (a part of haemoglobin in red blood cells). The liver is responsible for clearing the blood of bilirubin. It does this by the following mechanism: bilirubin is taken up into hepatocytes, conjugated (modified to make it water-soluble), and secreted into the bile, which is excreted into the intestine.
Increased total bilirubin causes jaundice, and can signal a number of problems such as internal hemorrhage, cirrhosis or viral hepatitis and obstruction of bile ducts.

Remove copper, chromium, cobalt, nickel, aflatoxin at liver

DO LIVER CLEANSES